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It has also been reported that homocysteine level is related to the extent of atherosclerosis in coronary and peripheral arteries (Chao et al, 1999b

doi: 10.3389/fchem.2014.00061

J Physiol 195 : 481492

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Furthermore, a prior preclinical investigation revealed that the Gln-Glu cycle is pathologically upregulated in a murine model of autism, contributing to E/I imbalance and the manifestation of autism-like behaviors [18]